Following its immediate negative reception, Rick Perry's 2012 presidential campaign advertisement ' Strong' garnered over 600,000 dislikes within five days. Measurement of dislikes on YouTube has been of academic and political interest.

The video was reinstated three months later and has not been taken down since. 'Friday' amassed over three million dislikes before the video was taken down in June 2011. In March 2011, 'Baby', which then had 1.17 million dislikes, was surpassed by the video for Rebecca Black's ' Friday', yielding more than 1.2 million dislikes. As of July 9, 2021, YouTube Rewind 2018 has over 7.1 million more dislikes than Justin Bieber's Baby. On December 13, 2018, YouTube Rewind 2018: Everyone Controls Rewind became the most disliked video on the video sharing platform, with 15 million dislikes rapidly surpassed the music video for Justin Bieber's song ' Baby', which entered the Guinness World Records book as the most disliked video on YouTube and on the Internet. YouTube Rewind 2018: Everyone Controls Rewind surpassed 'Baby' to become the most-disliked YouTube video within a week of being uploaded. As of OctoberВ 2020, Cocomelon вЂ“ Nursery Rhymes has the most videos in the top 50 with eleven, while YouTube has three and Jingle Toons have two.

For instance ' Despacito', ' Baby Shark Dance', and ' Gangnam Style' all appear on this list, but appear in the list of most-liked YouTube videos as well. Note that dislike count does not indicate the true unpopularity of videos, which is better represented by dislike percentage, also provided in the table. Of the 50 videos in this list, 6 also appear in the list of most-viewed YouTube videos and 4 appear in the list of most-liked YouTube videos. This feature serves as a replacement for the previous five-star rating system, which was found to be ineffective because of the rare selection of ratings from two to four stars. YouTube implemented a like and dislike button on video pages in 2010 as part of a major site redesign. The dislike count is taken directly from the page of the video itself. This list of most-disliked YouTube videos contains the top 50 videos with the most dislikes of all time, as derived from YouTube charts.

YouTube Rewind 2018 is the most disliked video on YouTube, receiving over 19 million dislikes since its upload on December 6, 2018.

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